The glucose-dependent mechanism means that when blood sugar levels are normal, insulin secretion is not excessively stimulated, providing a safer metabolic profile than some older diabetes treatments
And unlike other diets, GLP-1s have something like a built-in guardrail, with users citing specific cravings and aversions
And sure, we've had some people that have had an upward of 40 or 50 pounds to lose, but it's really, it's just, I think reaffirming to what my experience is seeing, who is coming and contacting us, but also us developing messaging and things based on what I know is huge
Patients reporting unexplained severe abdominal pain, nausea with vomiting, or confirmed pancreatitis diagnoses in the past year should not initiate semaglutide without gastroenterology clearance
Future obesity treatment may segment patients by metabolic phenotype, comorbidities, weight-loss targets, liver fat burden, cardiovascular risk, and treatment tolerance