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29 Collectively, these insights reinforce that autophagy is neither merely a degradation pathway nor a binary process but a carefully tuned homeostatic program that determines whether the myocardium adapts or deteriorates under stress

Nelson Textbook of Pediatrics (20th ed.)

The liver is constantly exposed to toxins, pollutants, and metabolic byproducts that generate harmful free radicals, leading to oxidative stress and cellular damage