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New evidence has indicated that mtDNA and mitochondrial extrusion via platelet activation through FcRIIA stimulation induces a circulatory autoantigenic load that ultimately leads to SLE pathogenesis (134, 135)
Synergistic activity of interleukin-17 and tumor necrosis factor-alpha enhances oxidative stress-mediated oligodendrocyte apoptosis
Frequency: Typically 3 treatments 4-6 weeks apart, then maintenance treatments every 4-6 months
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