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[2] The gut microbiome connection is worth noting in this context

They lower blood sugar through several coordinated effects, including 13: Increasing insulin release when blood sugar rises Reducing glucagon, which would otherwise raise blood sugar Slowing gastric emptying, which helps limit post-meal spikes Because these effects are glucose-dependent, the risk of hypoglycemia is relatively low compared to some other diabetes medications

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Initially developed for managing Type 2 diabetes, these drugs have surged in popularity thanks to their notable weight loss effects, often being prescribed off-label for obesity