Collectively, animal models are limited in their ability to accurately replicate human reproductive physiology, alongside inherent ethical and technical constraints [47]
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Current research continues to build on these established foundations while exploring new territory
That does not mean the number should be dismissed
Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Losos M, Tugwell P: The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses