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Receiver Operating Characteristic (ROC) analysis revealed that vanillic acid and N-hydroxy-isoleucine were the highest discriminative metabolites with an AUC value of 1 and also 2-aminobenzoic acid and picolinic acid showed high discriminative ability with an AUC of 0.995 and these might serve as potential prognostic biomarkers to monitor the progression of CKD to ESKD (Dahabiyeh et al., 2023)

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The Role of Digital Monitoring In order to make this vision possible, the ability to accurately monitor dosing within clinical trials is critical

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