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The intracellular lactate dehydrogenase (LDH) activity of living cells is relatively constant during the culture, while impaired cells lead to LDH leakage to the culture medium ( 2 O 2 , either in the presence or absence of peptides, was determined by using the spectrophotometric method

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Applying these substances directly to the affected area avoids systemic effects associated with oral and intravenous medications