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The percentage of adult patients prescribed a GLP-1 drug increased from 2019 to 2024 (Figure 1)

These medications work by curbing cravings and regulating your body's natural processes to promote weight loss

Multiple attempts to improve outcomes by intensifying antibiotic regimens most recently the HARVEST trial's test of high-dose rifampicin in 2025 have also failed to improve survival

The downstream effect of this slowing is that GLP-1s reduce the speed at which food passes through the body, thereby delaying its conversion into waste

Contact your healthcare provider if you notice sustained increases in your resting heart rate above 100 beats per minute, blood pressure readings consistently above 140/90 mmHg, rapid or unexpected weight loss exceeding two pounds per week, persistent inability to eat adequate amounts of food, or worsening mental health symptoms including anxiety, depression, or suicidal thoughts