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GSH is primarily synthesized intracellularly through two consecutive reactions catalyzed by -glutamylcysteine synthetase (Gsh1 in eukaryotes and GshA in prokaryotes, encoded by GSH1 and gshA , respectively) and glutathione synthetase (Gsh2 in eukaryotes and GshB in prokaryotes, encoded by GSH2 and gshB , respectively)
Senescence & Ageing Research Selected for experimental work focused on cellular senescence, stress-response pathways and ageing-related signalling
N -acetylcysteine"
Mechanistic studies suggest that it binds in a manner similar to amylin, affecting cellular signaling and neuroendocrine pathways
Son YJ, Phue JN, Trinh LB, Lee SJ, Shiloach J
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