Along with the heterogeneity of the disease and the lack of reliable biomarkers, the problem for developing specific treatments for PD is its multiple pathophysiological mechanisms, many of which are common to the mechanisms of T2DM development, including brain insulin resistance, impaired energy and glucose metabolism, mitochondrial dysfunction, chronic systemic inflammation, neuroinflammation, impaired lysosome function, and oxidative stress [56, 57]
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It may neutralise free radicals that cause oxidative stress and skin damage
CagriSema is an investigational once-weekly injectable weight-loss medication from Novo Nordisk that combines two active peptides, semaglutide and cagrilintide, in a single dose