The growth of GLP-1 use has also led to early acquisitions: in 2023, Weight Watchers acquired Sequence, a Series A telehealth company that prescribes GLP-1 drugs and provides support comprehensive services, for $132M
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Vials are lyophilized, sealed under argon, stored at -20C until refrigerated shipping
The change in RER upon insulin stimulation did not correlate with the change in RER measured during incremental submaximal cycling (r = -0.075, p = 0.723)
In theory, exogenous KLOW administration should enhance insulin sensitivity by improving GLUT4 translocation, reduce oxidative stress via upregulation of superoxide dismutase, and support mitochondrial biogenesis through AMPK pathway activation