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Advanced human model systems, especially SC-islets, are essential for establishing causal mechanisms, enabling researchers to link genetic risk, viral stressors, and immune responses in a human-relevant context and guide the development of targeted preventive therapies

These studies did not reveal an increased incidence of haematological malignancies compared to placebo groups

Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship

Romano, A., Tempesta, B., Micioni Di Bonaventura, M

The net potential of these molecular events is posited to be an environment more favorable to cell survival, in which proliferative signals outweigh apoptotic triggers