Next, in our isolated heart model of IRI (Figure 8B), we show that a 20-minute perfusion with GLP-1 (6 nM) improved functional LVDP recovery following IRI as compared with buffer-treated controls (52.4% 2.7% vs
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This diversity underscores its clinical significance and highlights the complexity of the underlying mechanisms, which may involve multifactorial interactions such as inflammation, neuronal dysfunction, disruptions in the gut-brain axis, and metabolic disorders