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Popular examples include: GLP-1 medications affect weight in several ways: These factors result in significant weight loss , often 1020% of total body weight

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Protocol phase 4: maintenance (months 6 through 12 and beyond) Once your tirzepatide dose is stable at maintenance level and your weight loss has begun to plateau, thyroid monitoring can decrease to every 3 to 6 months for the remainder of the first year, then annually if levels remain stable

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Further studies are needed to clarify potential associations between GLP-1 RAs and some recent concerns related to their safety