Data shows that urinary ferritin is closely linked to tubular injury, and it often rises earlier than the appearance of proteinuria
Mugler, J
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Its cysteinyl thiol group neutralizes reactive oxygen species, donates electrons in glutathione peroxidase reactions, and forms conjugates with electrophilic xenobiotics via glutathione S-transferases
This is supported by translational data indicating that blocking nitro-oxidative stress, inflammatory and neurotoxic pathways with selective antioxidative compouds may alleviate depressive-, anxiety-, and chronic fatigue-like behaviors [25, 26, 30, 35,36,37,38,39,40]