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Both drug classes are under scrutiny

Rat liver cytosolic GSH has a half-life of 23 hours [8], and the daily turnover for GSH is estimated to be higher than cysteine turnover in the body protein pool, around 40 mmol per day [21]

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Acknowledgements This work was partially supported by grants from JSPS (KAKENHI Grant Numbers JP21K08032 and 24K11270) to KS