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One of the key non-genomic actions of estrogen is the activation of second messenger systems, such as cyclic AMP (cAMP), protein kinase A (PKA), and phosphatidylinositol-3-kinase (PI3K) [72,74]

Stress 15 , 7484 (2012)

Alarcn-Ars D, Recasens A, Galofr M, Carballo-Carbajal I, Zacchi N, Ruiz-Bronchal E, Pavia-Collado R, Chica R, Ferrs-Coy A, Santos M et al (2018) Selective -Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinsons Disease

Antioxidant and Anti-Inflammatory Signaling# GHK-Cu quenches hydroxyl radicals, chelates reactive iron (blocking Fenton-reaction damage), suppresses NF-B signaling, and downregulates pro-inflammatory cytokines like IL-6 and TNF-