In the heart, zinc enhances cardiac mitochondrial function during reperfusion by ERK-dependent phosphorylation of STAT3 at Ser727, which translocates to mitochondria to upregulate ND6 and inhibit succinate dehydrogenase, reducing ROS generation 152
Given widespread, unofficial use, reporting appears limited
For retatrutide , the 2023 New England Journal of Medicine phase 2 trial used doses of up to 12 mg weekly, with a structured escalation schedule beginning at lower doses and increasing incrementally over a period of weeks
These disorders included attention-deficit hyperactivity disorder (ADHD), major depressive disorder, posttraumatic stress disorder, autism spectrum disorder, Tourette syndrome, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and anorexia nervosa
Theres a lot to consider