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PICOS framework and eligibility criteria to provide methodological clarity, the research scope and eligibility criteria were strictly defined using the PICOS framework: Population: adults with obesity or overweight (with or without diabetes) or adults with type 2 diabetes mellitus (T2DM)

However, when digestion slows down significantly, it can lead to common gastrointestinal side effects like bloating, nausea, and constipation

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Feng J.N., Shao W., Jin T

We emphasize that while semaglutide GLP-1 can be a powerful aid, combining the treatment with a nutritious diet and regular physical activity can further enhance its effectiveness