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Diabetes care 29 , 435449 (2006)

The most common study treatment-related adverse effects were GI disorders such as vomiting, abdominal distention, and nausea, however, mostly of mild intensity

Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study)

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