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Gut Hormone Implicated in NMOSD-Related Brain Inflammation The gut hormone glucagon-like peptide 1 (GLP-1) and its receptor (GLP-1R) may contribute to brain inflammation and nerve overactivity in patients with neuromyelitis optica spectrum disorder (NMOSD)

Clinical guidelines, as the post describes them, favor risk stratification with close monitoring over automatic exclusion

On August 15, 2025, the FDA granted accelerated approval to Wegovy (semaglutide 2.4 mg) for treating adults with non-cirrhotic MASH and moderate to advanced liver fibrosis

And people gain the weight back when they come off it. Costs for five of the GLP-1 drugs Ozempic, Mounjaro, Wegovy, Zepbound, and Saxenda topped $300 million for Boston-based Blue Cross last year, more than double what it spent in 2023

10.1016/j.cub.2018.05.094 196 SongZ