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131 This is consistent with the data in humans showing that a low-protein diet (5E% protein) increased plasma FGF21 concentrations by 171% over 4 weeks despite caloric overfeeding

Singly-housed rodents may have increased adiposity 101 and, moreover, singly-housed mice in standard caging can engage in coprophagy of their own feces that may impact their cecal microbiome 102

Pediatric Dermatology 82 Sept: 177-180

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Patients characteristics (age, sex, education, residency, body mass index, employment status, smoking status, depression, and multimorbidity) were included as covariates while Bonferroni correction and a minimum node sample size of 400 were imposed on the model to avoid model overfitting