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Fragmented ECM components like fibronectin and biglycan further act as damage-associated molecular patterns (DAMPs), engaging TLR2/4 on macrophages and enhancing cytokine release (139)

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Nutrition 26:112119 Kandil S, Brennan L, McBean GJ (2010) Glutathione depletion causes a JNK and p38 MAPK -mediated increase in expression of cystathionine--lyase and upregulation of the transsulfuration pathway in C6 glioma cells

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While human clinical trials remain limited, the existing body of evidence suggests BPC-157 may offer significant benefits for injury recovery, gut health, and tissue regeneration when used under proper medical supervision