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Current evidence is inconclusive, with some studies suggesting that phytoestrogens may help modulate hormonal balance and alleviate symptoms, while others raise concerns about their proliferative potential on estrogen-sensitive tissues [89,90,91]

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Consistent with the above bioinformatic analyses, these results further confirm that human IDD is characterized by a redox imbalance, ferroptosis activation, and inflammatory stress, suggesting an intricate interplay among these factors throughout the IDD cascade

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