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The trial excluded individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)

Its wide range of benefits, coupled with a lack of reported side effects, make it a promising frontier in peptide-based therapy.

For instance, in a pooled analysis of clinical trials, patients treated with semaglutide showed a slightly higher rate of gallbladder disorders compared to those on placebo or other diabetes medications

S6, panels A-E), as well as increased expression of several -catenin target genes 36 (Fig