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In a 72-week clinical trial studying Zepbound (15 mg) in patients without diabetes and with BMI 30, or BMI 27 with a weight-related condition, the average weight loss was 20%, when paired with diet and exercise changes (compared to 3.1% with diet and exercise alone)

Many new GLP-1 drugs are in development pipelines

Therefore, the considerable effects observed may not reflect or ameliorate all the conditions that make up metabolic syndrome, including abdominal obesity, high blood glucose, high blood sugar, high LDL levels, and low HDL levels

because prevention is better than cure