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Healthy dietary patterns such as the Mediterranean diet, while having limited effects on BCAA levels, may counteract the harmful effects of BCAAs through other mechanisms (87)

These effects contribute to prolonged satiety and weight loss but also cause nausea, vomiting, and abdominal discomfort, particularly during dose escalation

MFN, PARKIN, PINK, MIEF, UCP-1 and Wnt-3 ) via the RT-qPCR technique (Fig

However, related studies show that the activation of NRF2 alleviates the occurrence and development of AD by enhancing the antioxidant defense, improving mitochondrial function, inhibiting neuroinflammation, and inhibiting ferroptosis (Qu et al., 2020)