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Declaration of Generative AI and AI-assisted technologies in the writing process During the preparation of this work the authors did not use any generative AI and AI-assisted technologies in the writing process

According to TCM, your liver stores blood

Slows aging - It is well established that NAD levels decline with age

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3.1.1.4 Grape seed proanthocyanidin extract (GSPE) GSPE, a natural bioactive compound from plant, exhibits great therapeutic properties through inhibiting oxidative stress and promoting mitochondrial biogenesis ( via AMPK-Sirtuin-1-PGC-1-TFAM signaling pathway ( 3.1.2 Sirtuin activators 3.1.2.1 Resveratrol Resveratrol, a natural compound extracted from the berries of Vaccinium species, can activate sirtuin-1, sirtuin-3, and sirtuin-5 (Xia et al., 2017