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When you give a patient a chemotherapeutic, its kind of an arms race: Youre killing the cancer cells, but youre also killing the rest of the body because so many things are similar

Non-diabetic patients need a specialized approach to their care

Furthermore, metformin was shown to mitigate the effects of testosterone-induced hormone receptor expression, and restore testosterone and HOXA10 expression levels (Ohara et al., 2021)

The second mechanism involves inhibition of clonogenic cell growth, potentially via downregulation of RRM2 and DNA damage, leading to accumulation of DNA breaks and cell cycle blockade

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