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The NADPH produced via the PPP is required for the production of glutathione (GSH) (53, 54)

However, ROS generated during chemotherapy may be associated with events such as cardiotoxicity, nephrotoxicity, and neurotoxicity and may interfere with normal cells and tissues

Manufacturing these peptide-based biologics requires highly specialized production facilities, complex formulation processes, stringent quality controls, and substantial capital investment, limiting the ability of manufacturers to rapidly scale output

may be attributable to differences in study populations, GLP-1 type, and the extent of weight loss achieved

Efficacy and safety of empagliflozin for type 2 diabetes: a systematic review and meta-analysis