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Fat is stored mainly in adipocytes in subcutaneous tissue and in the intraperitoneal cavity, although the liver and other organs of the body may accumulate significant amounts of lipids in obese persons

Drug Delivery, 20 , 247251

El Framingham Offspring Study demostr que la obesidad reduce en ms de cinco aos la expectativa de vida libre de enfermedades cardiovasculares y metablicas(9)

For example, in liver, exendin-4 treatment activates GL-1R receptor and enhances insulin action [7]