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The estimated mean change in body weight from baseline to week 68 was 13.7% in the cagrilintide-semaglutide group and 3.4% in the placebo group (estimated difference, 10.4 percentage points

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This is indicative of skewing toward a proresolving macrophage phenotype because a reduction of CD80 is a distinctive mechanism of active resolution, in agreement with the reduction in erythrophagocytosis (40)