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Even so, moving from this biochemical function to clinical outcomes is not always straightforward: the evidence can be heterogeneous and depends on dose, duration, the population studied and lifestyle variables

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Final Thoughts GLP-1 medications can be powerful tools for weight loss, but they work best when combined with healthy habits that last beyond treatment

225 In MASLD animal models, quercetin reduces hepatic triglyceride levels, increases AMPK phosphorylation, and improves insulin sensitivity, as reflected by HOMA-IR index reductions