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Neuroprotective compounds that enhance mitochondrial function, reduce oxidative stress, and support proteostasis are also being explored in preclinical and early clinical studies [39, 53, 54]

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Phasic inhibition An inhibitory signal that relies on postsynaptic receptors closely apposed to presynaptic release sites, is typically coupled to presynaptic action potentials and is brief (tens to hundreds of milliseconds) in duration

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