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The cardiovascular outcomes data expected from dual GLP-1/amylin therapies offers a great opportunity for differentiation of the product in the market on a basis of greater cardiovascular risk reduction than the current GLP1 monotherapy standards

However, LXR receptors are widely distributed across multiple tissues and cell types, particularly in immune and metabolic regulatory pathways

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Portfolio Strategy in the Wake of GLP-1: Dongoski regards GLP-1 discussion as another reasonfor some companiesto re-evaluate business portfolio, product formulations and target consumers