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A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis

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Nrf2 activation regulates antioxidant responses to modify cellular redox states from predominantly pro-oxidant to antioxidant, and, in an antioxidant environment, macrophage phenotypes shift from M1 pro-inflammatory to M2 anti-inflammatory, reducing the probability of cytokine storms, ARDS, and lethality (Tan et al., 2016

A healthy level of Glutathione is crucial because the degenerative process of autoimmune disease destroys the mitochondria in affected cells, such as thyroid tissue in Hashimotos