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3rd, Vyushkov, D., Yang, Y., Bendell, J., & Verma, U

Autoimmune Conditions Commonly Associated With Chronic Pain Many autoimmune and inflammatory disorders can contribute to persistent pain, including: Rheumatoid arthritis Psoriatic arthritis Lupus Hashimotos thyroiditis Sjogrens syndrome Inflammatory bowel disease Small fiber neuropathy Fibromyalgia-like inflammatory syndromes Undifferentiated connective tissue disease The Role of Neuroinflammation in Chronic Pain One of the most important emerging concepts in pain medicine is the role of neuroinflammation

Several decisions were close, and the committee heard substantial disagreement about chemical characterization, peptide-related impurities, immunogenicity, carcinogenicity signals or uncertainty, the limited quantity and quality of human evidence, and whether existing FDA-approved therapies already address the proposed uses

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