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Observational and Real-World Data Registry analyses and retrospective reviews have not demonstrated higher pregnancy incidence among women prescribed GLP-1 RAs compared with matched controls

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Combined treatment with high-dose ACEI and sitagliptin significantly increased BP by elevating the expression of substance P, while low-dose ACEI had no such effect ( Renal Mechanisms Underlying the Action of DPP-4i on Hypertension Various factors act upon the renal system and cause water-sodium retention, thus increasing cardiac output and peripheral vascular resistance

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