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Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes

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This, and high blood pressure and diabetes can be particularly hard on your kidneys

Health Canada states that SGLT-2 inhibitors are drugs designed to lower blood sugar in adults with Type 2 diabetes by helping remove excess sugar from the body through the urine, while DPP-4 inhibitors are also used to treat Type 2 diabetes in adults alongside an appropriate diet and exercise to control blood sugar. In some cases, DPP-4 inhibitors are also used with another anti-diabetic drug