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A second study evaluated an 8-week protocol combining low-frequency high-intensity interval training (HIIT) with CIT supplementation in 30 sedentary older men

[87] Pistone G, Marino A, Leotta C, DellArte S, Finocchiaro G, Malaguarnera M.Drugs Aging

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In contrast, several studies included in this review that enrolled younger individuals or participants with milder symptom profile have documented improvements following EPA/DHA supplementation, suggesting that age, developmental stage, and baseline severity may critically modulate treatment responsiveness