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adult population (BMI of 30 or higher) peaked around 2017-2020 (and may be declining slowly),[2] rates of severe obesity (BMI or 40 or higher) continue to climb steadily (currently around 10%)

Although the brain represents only a small percentage of total body weight, it consumes more than 20 percent of the body's energy

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Activation of downstream signaling: The binding of Dihexa to c-Met receptor activates downstream signaling pathways, including the mitogen-activated protein kinase (MAPK) pathway and the phosphoinositide 3-kinase (PI3K) pathway