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General overview of HSP70s Members The term HSP70 refers to a family of chaperones with a molecular weight of approximately 70 kDa, consisting of 13 members in humans with distinct functions and intracellular localizations (Kampinga et al., 2009), derived from corresponding genes, whereas HSPA7 is usually considered as a pseudogene (Ding et al., 2021), with ambiguous data on HSPA7 role (Li et al., 2022)

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however, brain exposure to Salvianolic acid A was markedly elevated in I/R rats compared to sham controls (fold change of 9.17), indicating that the increased exposure to Salvianolic acid A facilitated its neuroprotective effect (Feng et al., 2017)