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Importantly, individuals expressing greater body dissatisfaction and weight-related concerns appear most interested in pharmacologic treatment, and demand for these agents extends beyond those with medical indications

Diagnostic and Statistical Manual of mental Disorders: DSM-V

In line with this, the gastric emptying delay induced by GLP-1RAs is dependent on the presence of GLP-1Rs on these vagal afferents (Imeryuz et al., 1997)