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Consultation: If you're pregnant, nursing, or have any medical conditions, consult your doctor before starting any new supplement regimen

Reference Xie Y et al

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Protein Synthesis Supplemental creatine is demonstrated to upregulate pathways linked to muscle protein synthesis, helping to stimulate growth when combined with sufficient protein

In a follow-on study, general obese participants were administered either placebo or a dose-titrated regimen of MK-0493, in which participants received 400 mg PO QD of MK-0493 for seven days, with dose escalations of 200 mg every seven days until a final dose of 1000 mg PO QD was attained (48)