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As weight decreases, many thyroid patients require a lower dose of levothyroxine or other replacement hormones because their body's metabolic needs decrease

157 , A5719 (2013)

These mutations within the chromatin binding region of L2 prevent efficient tethering of L2 to mitotic chromosomes resulting in accumulation of vesicle-bound L2/vDNA at the Golgi compartment rather than localizing to the nucleus [26]

Many participants discontinued therapy at some point, and in most the episodes returned, later resolving again on renewed therapy

Myocardial Reverse Remodeling - Hellawell - 2012 - Cardiovascular Therapeutics - Wiley Online Library