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ARA-290 peptide is sourced by research teams investigating the innate repair receptor a heteromeric receptor complex distinct from the classical erythropoietin receptor and its associated intracellular signaling cascades in controlled in vitro environments

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Oxidative stress is associated with induction of neurosteroid biosynthesis in the human brain (284), and TSPO ligands ( N , N -dialkyl-2-phenylindol-3-ylglyoxylamides) that also show anxiolytic activity promote a reduction in oxidative stress and pro-inflammatory enzymes in glial cells via promotion of neurosteroid synthesis (133)

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