I can speak from experience, as well as the science, studies, and data
Circulating endogenous GLP-1 has a half-life of 1-2 minutes, being rapidly inactivated by dipeptidyl-peptidase IV
Persistent dark urine despite hydration, tea-coloured urine, or accompanying jaundice requires prompt medical evaluation to exclude gallbladder disease, hepatobiliary disorders, or acute kidney injury
It should also be noted that an oral form of semaglutide was developed by adding an agent to the drug formulation, which increases intestinal permeability, sodium N-(8-(2-hydroxybenzoyl)amino)caprylate (SNAC), but the lower bioavailability of the molecule requires daily administration to achieve glycemic control equivalent to that obtained by the form administered subcutaneously
Noom Telehealth for Branded Meds is available more broadly