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Although uterine expression levels of estrogen receptor , G protein-coupled estrogen receptor, and steroid synthase were upregulated in the high-dose group, the decreased expression of connexin 43 and alkaline phosphatase as well as the increased expression of insulin-like growth factor-binding protein three and monoamine oxidase were consistent with decreased estrogen signaling and lower uterine weights

References Raun K, et al

This phenomenon was accentuated following PA treatment in both SUM-159 and SUM-159-CD36 cells but not in MCF-7 and MCF-7-CD36 cells

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PdZn/CoSA-NC nanozymes with highly efficient SOD/CAT activities for treatment of osteoarthritis via regulating immune microenvironment