received advisory/consulting fees and/or other support from Altimmune, AstraZeneca, Bayer, Biomea, Boehringer Ingelheim, Carmot Therapeutics, Cytoki Pharma, Eli Lilly, Intercept, Janssen/Johnson & Johnson, Mannkind, Mediflix, Merck, Metsera, Novo Nordisk, Pharmaventures, Pfizer, Regeneron, Sanofi, Shionogi, Structure Therapeutics, Target RWE, Terns Pharmaceuticals, The Comm Group, Valeritas, WebMD and Zealand Pharma
Use a new, sterile syringe and needle for every injection
At therapeutic doses, tirzepatide has shown greater weight loss outcomes in head-to-head trials
For comprehensive overview of all options, check our comparison of weight loss medications in 2026
Semaglutide is FDA-approved and belongs to a class of drugs that helps manage blood sugar levels and can support weight loss