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Impact of GLP-1 on Obesity Glucagon-like peptide-1 (GLP-1) receptor agonists, initially designed for type 2 diabetes (T2D), have emerged as a revolutionary treatment for obesity owing to their significant impact on weight reduction and metabolic control

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Heavy drinkers with depressive symptoms typically exhibit (1) later age of MDD onset (post-25 years), (2) predominance of somatic symptoms (e.g., fatigue, insomnia) over cognitive rumination, and (3) partial responsiveness to selective serotonin reuptake inhibitors (SSRIs), which may reflect underlying serotonergic deficits compounded by ethanols neurotoxic effects (Pedrelli et al

In univariable analyses, sex, reporting country, and drug category were significantly associated with the occurrence of ICI-related adverse events